Two things about Alex Trebek for me...
1. I watched with my kids and we all tried to answer the questions. It always heavily favored me, until both my kids got older. Lately, I'm struggling to win, and I love it.
2. My Mother-In-Law, who I considered my other Mother. A great person, took me in as a son, and is a better person than ALL of us. She died of the same cancer. I was holding her hand when she passed in my house. It's unlikely that I'll ever meet someone as pure and good as her, but I strive every day to live up to that standard.